Myogenic Determination and Differentiation of Chicken Bone Marrow-Derived Mesenchymal Stem Cells under Different Inductive Agents.

KEGG pathway analysis revealed that DEGs were enriched in myogenic differentiation-associated pathways containing the PI3K-Akt signaling pathway, the TGF-β signaling pathway, Arrhythmogenic right ventricular cardiomyopathy, dilated cardiomyopathy, and hypertrophic cardiomyopathy, which suggested that BM-MSCs differentiated into a muscle-like phenotype under 5-Aza-treatment. In summary, the study lays the foundation for constructing a myogenic determination and differentiation model in chicken BM-MSCs.

For the study's cell samples, Countstar (model not specified) provided cell-count measurements during growth assessment in the 2022 Animals: an open access journal study.