Multicolor fluorescence encoding of different microRNAs in lung cancer tissues at the single-molecule level.
Chemical science
Li CC, Chen HY, Luo X, Hu J, Zhang CY.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2021
Cancer Research
No items found.
Key Finding
After magnetic separation and exonuclease cleavage, the amplified products release abundant Cy5 and Cy3 fluorescent molecules which can be simply monitored by single-molecule detection, with Cy3 indicating miR-21 and Cy5 indicating miR-155.
Countstar Connection
Countstar (model not specified) measured cell numbers in the study's cell samples during quality assessment in the 2021 Chemical science study.