Multi-omics analysis of human tendon adhesion reveals that ACKR1-regulated macrophage migration is involved in regeneration.
Bone research
Zhang X, Xiao Y, Hu B, Li Y, Zhang S, Tian J, Wang S, Tao Z, Zeng X, Liu NN, Li B, Liu S.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2024
Immunology
Single-Cell Analysis
No items found.
Key Finding
As, the authors found that SPP1 + macrophages, RGCC + endothelial cells, ACKR1 + endothelial cells and ADAM12 + fibroblasts participated in tendon adhesion formation. Compared with WT chimeras, the decline of FOLR2 + macrophages was also observed, indicating that ACKR1 was specifically involved in FOLR2 + macrophages migration.
Countstar Connection
Countstar (model not specified) measured cell viability in the study's cell samples before single-cell analysis in the 2024 Bone research study.
