MiR-92b-3p Inhibits Proliferation of HER2-Positive Breast Cancer Cell by Targeting circCDYL.
Frontiers in cell and developmental biology
Liang G, Ling Y, Lin Q, Shi Y, Luo Q, Cen Y, Mehrpour M, Hamai A, Li J, Gong C.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2021
Cancer Research
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Key Finding
CircRNA pull-down and miRNA sequencing demonstrated binding between miR-92b-3p and circCDYL. Their expression levels were associated with clinical outcomes in HER2-positive breast cancer, while the reported functional analyses supported circCDYL targeting as the mechanism underlying miR-92b-3p-mediated growth inhibition.
Countstar Connection
The study used a Countstar instrument for cell-count assessment in cell suspensions during the study's growth assessment.