MiR-22-3p suppresses NSCLC cell migration and EMT via targeting RAC1 expression.
Functional & integrative genomics
Wang X, Wang X, Jiang T, Zhang Z, Xie N, Yang G.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2023
Cell Counting & Viability
No items found.
Key Finding
Mechanistically, the authors demonstrated that miR-22-3p suppressed the cell migration and EMT via downregulation of RAC1 because the inhibitory effect of miR-22-3p on cell migration and EMT of NSCLC cells was reversed by RAC1 overexpression.
Countstar Connection
Countstar (model not specified) supported assessment of cell numbers in the study's cell samples during migration assessment in the 2023 Functional & integrative genomics study.
