Mincle receptor in macrophage and neutrophil contributes to the unresolved inflammation during the transition from acute kidney injury to chronic kidney disease.

Recent studies have demonstrated a strong association between acute kidney injury (AKI) and chronic kidney disease (CKD), while the unresolved inflammation is believed to be a driving force for this chronic transition process. Mincle-deficient mice exhibited reduced renal injury and fibrosis following AKI.

Within the study, Countstar Rigel S2 measured cell viability in single-cell suspensions during preparation for single-cell or single-nucleus analysis.