Mifepristone (RU486) inhibits dietary lipid digestion by antagonizing the role of glucocorticoid receptor on lipase transcription.
iScience
Ma P, Zhang Y, Liang Q, Yin Y, Wang S, Han R, Huo C, Deng H.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2021
Cell Counting & Viability
No items found.
Key Finding
The study found that mifepristone (RU486) prevents lipid digestion both in flies and mice. Further studies showed that the pancreatic lipase Pnlip is a direct transcriptional target of GR in pancreas tissues.
Countstar Connection
Countstar (model not specified) measured cell numbers in the study's cell samples during quality assessment in the 2021 iScience study.
