MicroRNA-155-5p suppresses the migration and invasion of lung adenocarcinoma A549 cells by targeting Smad 2.
Oncology letters
Lin J, Chen Y, Liu L, Shen A, Zheng W.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2018
Cancer Research
No items found.
Key Finding
The study indicated that transfection of miR-155-5p mimic significantly suppressed cell proliferation, migration and invasion of A549 cells, whereas its inhibition significantly promoted cell proliferation, migration and invasion of A549 cells, suggesting a potential therapeutic application of miR-155-5p in controlling lung cancer metastasis. Collectively, the findings suggest that miR-155-5p suppresses the proliferation, migration and invasion of A549 cells.
Countstar Connection
Countstar (model not specified) supported measurement of cell numbers in the study's cell samples during the study's migration assessment.
