SCIENTIFIC EVIDENCE

Microglial MS4A4A Protects against Epileptic Seizures in Alzheimer's Disease.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Jiang M, Li Q, Chen J, Li R, Yao J, Hu Y, Zhang H, Cai L, Luo M, Sun Y, Zeng W.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2025
Single-Cell Analysis
No items found.
Key Finding
The cytosolic fragment of Ms4a4a is anchored to the cytoskeletal components, supporting its critical role in mediating phagocytosis. Collectively, these findings identify Ms4a4a as a potential therapeutic target for managing seizures in AD treatment.
Countstar Connection
The study measured cell number and viability in the study's cell samples using Countstar (model not specified) before single-cell analysis for the reported research.
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