SCIENTIFIC EVIDENCE

Microglia-endothelial cross-talk regulates diabetes-induced retinal vascular dysfunction through remodeling inflammatory microenvironment.

iScience
Ben S, Ma Y, Bai Y, Zhang Q, Zhao Y, Xia J, Yao M.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2024
Single-Cell Analysis
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Key Finding
Exploration of intercellular crosstalk between microglia and ECs showed that diabetes-induced interactions mainly participated in the inflammatory response and vessel development, with colony-stimulating factor 1 (CSF1) and CSF1 receptor (CSF1R) playing important roles in early cell differentiation.
Countstar Connection
Cell-count and viability assessment in the study's cell samples was performed with Countstar Rigel S2 during preparation for single-cell or single-nucleus analysis.
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