SCIENTIFIC EVIDENCE

Micro RNA-175 Targets Claudin-1 to Inhibit Madin-Darby Canine Kidney Cell Adhesion.

Genes
Li X, Ma F, Wang S, Tang T, Ma L, Qiao Z, Ma Z, Wang J, Liu Z.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2024
Immunology
No items found.
Key Finding
There is evidence that the use of gene editing techniques to inhibit cell adhesion and establish an easily suspended cell line can improve vaccine yield; however, the mechanisms underlying MDCK cell adhesion are unclear. These findings contribute to a more comprehensive understanding of the regulatory mechanisms modulating cell adhesion and provide a basis for establishing suspension-adapted, genetically engineered cell lines.
Countstar Connection
Countstar (model not specified) supported measurement of cell numbers in cell suspensions during the study's growth assessment.
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