SCIENTIFIC EVIDENCE

Maternal cholesterol deficiency predisposes congenital heart defects risk.

Signal transduction and targeted therapy
Gu Y, Gao J, Lv H, Zhou Y, Jiang T, Guo J, Ma W, Cheng Y, Chi X, Xi Q, Ye K, Du J, Li J, Wang C, Dai J, Ma H, Jin G, Lin Y, Shen H, Hu Z.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2025
Bioprocessing
Immunology
No items found.
Key Finding
Both treatments led to a significant increase in the incidence of CHD in offspring. Most intriguingly, maternal dietary intervention to increase cholesterol intake effectively reduced the risk of CHD in Cyp51 I383V mutant offspring.
Countstar Connection
Cell concentration and viability were quantified in the study's cell samples with Countstar Rigel S2 before single-cell analysis for the reported research.
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