Lung Single-Cell Transcriptomics Offers Insights into the Pulmonary Interstitial Toxicity Caused by Silica Nanoparticles.
Environment & health (Washington, D.C.)
Li Y, Yao Q, Xu H, Ren J, Zhu Y, Guo C, Li Y.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2024
Immunology
Single-Cell Analysis
No items found.
Key Finding
Of note, both GEO database analysis and the experiments' validation indicated that Hsps, especially Hspd1, may be a key contributor to pulmonary interstitial injury, possibly through triggering oxidative stress, immune response, and disrupting protein homeostasis.
Countstar Connection
Cell number and viability were assessed in the study's cell samples with Countstar Rigel S2 during preparation for single-cell or single-nucleus analysis.
