SCIENTIFIC EVIDENCE

LncRNA SNHG7 Regulates Mesenchymal Stem Cell Through the Notch1/Jagged1/Hes-1 Signaling Pathway and Influences Folfirinox Resistance in Pancreatic Cancer.

Frontiers in oncology
Cheng D, Fan J, Qin K, Zhou Y, Yang J, Ma Y, Shi M, Jin J.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2021
Cancer Research
Stem Cell Research
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Key Finding
MSC co-culture enhanced the stemness and Folfirinox resistance in pancreatic cancer cells according to the findings. Finally, the findings showed that MSCs increased SNHG7 expression in pancreatic cancer cells, promoting the stemness and Folfirinox resistance via the Notch1/Jagged1/Hes-1 signaling pathway.
Countstar Connection
Countstar (model not specified) measured cell numbers in the study's cell samples during quality assessment in the 2021 Frontiers in oncology study.
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