LncRNA SNHG17 interacts with LRPPRC to stabilize c-Myc protein and promote G1/S transition and cell proliferation.
Cell death & disease
Liu JY, Chen YJ, Feng HH, Chen ZL, Wang YL, Yang JE, Zhuang SM.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2021
Cancer Research
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Key Finding
Analysis of human hepatocellular carcinoma (HCC) tissues revealed that SNHG17, LRPPRC, and c-Myc were significantly upregulated in HCC, and they showed a positive correlation with each other. The findings identify a novel SNHG17-LRPPRC-c-Myc regulatory axis and elucidate its roles in G1/S transition and tumor growth, which may provide potential targets for cancer therapy.
Countstar Connection
Researchers used Countstar (model not specified) to assess cell numbers in the study's cell samples during the study's growth assessment.
