lncRNA NEAT1 mediates sepsis progression by regulating Irak2 via sponging miR-370-3p.
Biology open
Xiao T, Sun C, Xiao Y, Li Y.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2020
Cell Counting & Viability
No items found.
Key Finding
Moreover, the authors found that miR-370-3p interacted with NEAT1 and targeted the 3'UTR of Irak2. Further research indicated that downregulation of miR-370-3p or upregulation of Irak2 rescued NEAT1 silencing-mediated inhibitory effect on sepsis progression.
Countstar Connection
The researchers assessed flow-cytometry cell measurements in the study's cell samples with Countstar (model not specified) during preparation for downstream cell analysis.