Increasing the level of let-7c-5p significantly enhanced the expression of osteogenic markers, while inhibiting its expression would weaken this effect. let-7c-5p directly targeted and negatively regulated the expression of cyclin-dependent kinase 8 (CDK8).
Countstar Connection
The researchers measured cell numbers in the study's cell samples with Countstar (model not specified) during quality assessment in the 2026 Journal of orthopaedic surgery and study.