let-7c-5p promotes fracture healing by downregulating CDK8.
Journal of orthopaedic surgery and research
Liu W, Zhang J, Chen X, Cheng B, Li Q, Li L, Yang H.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2026
Cell Counting & Viability
No items found.
Key Finding
Increasing the level of let-7c-5p significantly enhanced the expression of osteogenic markers, while inhibiting its expression would weaken this effect. let-7c-5p directly targeted and negatively regulated the expression of cyclin-dependent kinase 8 (CDK8).
Countstar Connection
The researchers measured cell numbers in the study's cell samples with Countstar (model not specified) during quality assessment in the 2026 Journal of orthopaedic surgery and study.
