LAPTM4B-YAP loop feedback amplification enhances the stemness of hepatocellular carcinoma.
iScience
Liao J, Wang J, Xu Y, Wu Y, Wang M, Zhao Q, Tan X, Meng Y, Wei L, Huang A.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2023
Cancer Research
Single-Cell Analysis
No items found.
Key Finding
Overall, the findings suggest that LAPTM4B forms a positive feedback loop with YAP, which maintains the stemness of HCC tumor cells and leads to an unfavorable prognosis for HCC patients.
Countstar Connection
Countstar (model not specified) measured cell viability in the study's cell samples before single-cell analysis in the 2023 iScience study.
