LAG3 blockade coordinates with microwave ablation to promote CD8 + T cell-mediated anti-tumor immunity.
Journal of translational medicine
Shao D, Chen Y, Huang H, Liu Y, Chen J, Zhu D, Zheng X, Chen L, Jiang J.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2022
Cancer Research
Immunology
Single-Cell Analysis
No items found.
Key Finding
Furthermore, the authors have reported that following microwave ablation (MWA), the expression of LAG3 is up-regulated in tumor microenvironment (TME), indicating that LAG3 is implicated in the regulation of immunosuppressive immune response, and combination therapy of MWA and LAG3 blockade can serve as a promising therapeutic strategy against cancer.
Countstar Connection
Researchers relied on Countstar (model not specified) for cell measurements in cell suspensions during preparation for single-cell or single-nucleus analysis.
