SCIENTIFIC EVIDENCE

Label-Free 3D Photoacoustic Imaging of Tumor Organoids for Volumetric Drug Screening.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Luo X, Chen M, Shan H, Yu X, Lin Q, Tao Q, Wei X, Lv C, Chen Z, Zhuo F, Zhu X, He J, Li Z, Fei C, Xu J, Su J, Chen Z, Zhao S, Chen X.

Publication Overview

Key findings, Countstar context, and access to the original paper.

2025

3D Culture

Cancer Research

Organoid Culture

Mira BF

Key Finding

Drug screening with cisplatin and temozolomide reveal that LFOPI-based organoid volume data correlates more strongly with viability trends (0.8627 and 0.9069) than traditional diameter-based (0.8190 and 0.7849). Additionally, immunotherapy drug screening demonstrates the capability of the system to precisely assess the 3D volumes of irregularly shaped organoids.

Countstar Connection

Countstar Mira BF supported assessment of live and dead cell numbers in tumor-cell samples within the 3D-culture workflow in the 2025 Advanced science study.

View paper ↗

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