KLF14 activates the JNK-signaling pathway to induce S-phase arrest in cervical cancer cells.
Frontiers in immunology
Du Y, Ye H, Lin M, Cao L.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2023
Cancer Research
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Key Finding
KLF14 overexpression induced S-phase arrest and inhibited cervical cancer cell proliferation in vivo. The effect depended on the KLF14 zinc-finger structure and involved activation of JNK signaling together with increased CDK2 and CCNA2 expression.
Countstar Connection
The study obtained cell-concentration measurements from the study's cell samples using Countstar (model not specified) during the study's growth assessment.