Interaction between CDC6 and Tmod3 accelerates resistance to paclitaxel through focal adhesion assembly.
Signal transduction and targeted therapy
Liu Y, Wang H, Zhan J, Sun J, Sun Y, Fu X, Lv D, Li X, Dong T, Lou H.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Cell Counting & Viability
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Key Finding
Overall, the study elucidate the mechanisms through which CDC6 functions as a key regulator of PTX resistance and provide a potential therapeutic strategy to increase PTX efficacy through the modulation of the cytoskeletal-adhesion axis.
Countstar Connection
A Countstar instrument quantified cell numbers in the study's cell samples during growth assessment in the 2025 Signal transduction and targeted therapy study.