Integrating real-time OUR monitoring with adaptive feeding for enhanced antibody production.
Bioresources and bioprocessing
Zhang XR, Ran Q, Zhang B, He YM, Zhao L, Tan WS, Ye Q.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Bioprocessing
Immunology
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Key Finding
Notably, OBCF enhanced pyruvate utilization and TCA cycle activity, promoted amino acid catabolism, and suppressed by-product accumulation. These metabolic improvements led to a 52% increase in specific productivity (Q P ) and a 32% increase in total antibody yield during LSP, along with reduced batch-to-batch variability.
Countstar Connection
The study used Countstar (model not specified) for cell-concentration, viability, and size assessment in the study's cell samples during quality assessment in the 2025 Bioresources and bioprocessing study.
