Insights into IAV Replication and Lipid Metabolism in Suspension-Adapted MDCK-STAT1-KO Cells.
Vaccines
Ye Q, Yao H, Xiao Z, Zhao L, Tan WS.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Microbiology
No items found.
Key Finding
However, the STAT1-KO cells showed a 2.39-fold higher release rate (750 virions/cell/h) and 3.26-fold greater RNA release for the H1N1 virus compared to wild-type cells. This study demonstrates the enhanced influenza virus production capacity of susMDCK-STAT1-KO cells, with significant improvements in viral yield, replication, and release efficiency.
Countstar Connection
Using Countstar (model not specified), the study assessed cell concentration, viability, and size in the study's cell samples during quality assessment in the 2025 Vaccines study.
