Inhibition of HBV Replication by a Fully Humanized Neutralizing Antibody In Vivo and In Vitro.
Acta naturae
Zhang Z, Ma Y, He Y, Wang D, Song H, Yue K, Zhang X.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Immunology
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Key Finding
The authors established an AAV/HBV mouse model and observed significant dose-dependent reduction in HBsAg and HBV DNA levels for both the medium-dose and highdose groups. The immunohistochemical staining data showed dose-dependent reduction in HBsAg expression in the liver, with high-dose group exhibiting minimal positive expression.
Countstar Connection
Cell numbers were measured in the study's cell samples with Countstar (model not specified) during quality assessment in the 2025 Acta naturae study.