Induction of oxidative stress, apoptosis and DNA damage by koumine in Tetrahymena thermophila.
PloS one
Ye Q, Zhang C, Wang Z, Feng Y, Zhou A, Xie S, Xiang Q, Song E, Zou J.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2019
Microbiology
No items found.
Key Finding
Mitophagic vacuoles were present in cells indicating induction of autophagy by this drug. Expression of ATG7, MTT2/4, CYP1 and HSP70 as well as the MAP kinase pathway gene MPK1 and MPK3 were significantly altered after exposed to koumine.
Countstar Connection
For the study's cell samples, researchers obtained cell-count measurements with Countstar (model not specified) during quality assessment for the reported research.
