Immunosuppression and phenotypic plasticity in an atlas of human hepatocholangiocarcinoma.

GZMK + CD8 + Tex cells exhibited higher infiltration of after treatment in H-ChC, the effector scores and expression of the immune checkpoints of them greatly increased after immunotherapy, which indicated that H-ChC might be more sensitive than HCC or iCCA to immunotherapy.

Countstar Rigel S2 supported cell number and viability measurement in the study's cell samples before single-cell analysis for the cancer-model experiments.