Immune signatures of megakaryocytes in persistent inflammation-immunosuppression and catabolism syndrome.
Acta biochimica et biophysica Sinica
Sun X, Nan K, Zhong Z, Liu Z, Miao C.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Immunology
Single-Cell Analysis
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Key Finding
Ligand-receptor analysis reveals dynamic interactions among MKs and T cells, B cells, natural killer cells, monocytes, and macrophages, suggesting a broad role of MKs in immune homeostasis. The findings establish MKs as essential components of the immune system in PICS and provide new insights into their potential as therapeutic targets for post-sepsis immune dysfunction.
Countstar Connection
The study obtained cell-viability measurements from the study's cell samples using Countstar (model not specified) during preparation for single-cell or single-nucleus analysis.
