Identification of genes contributing to cisplatin resistance in osteosarcoma cells.
FEBS open bio
Xie M, Dai H, Gu Q, Xiao C, Wang H, Lei Y, Wu C, Li X, Lin B, Li S.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2023
Cell Counting & Viability
No items found.
Key Finding
Therefore, understanding the molecular mechanisms of chemotherapy resistance in osteosarcoma cells is crucial for developing new therapeutic approaches and ultimately improving the prognosis of osteosarcoma patients. To identify genes associated with cisplatin resistance in osteosarcoma, the authors screened a large-scale mutant library generated by transfecting human osteosarcoma cells with a piggyBac (PB) transposon-based gene activation vector.
Countstar Connection
The researchers assessed cell numbers in the study's cell samples with Countstar (model not specified) during cell-culture monitoring.
