SCIENTIFIC EVIDENCE

Hypoxia-Induced Osteopontin-Positive Glioma-Associated Macrophages Facilitate Glioma Mesenchymal Transition via NF-κB Pathway Activation.

Cancer communications (London, England)
Yang J, Li X, Zhu X, Li Z, Chen X, Huang R, Yu M, Han B, Jiang T, Zhang C, Liu X.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2026
Cancer Research
Immunology
Stem Cell Research
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Key Finding
This study revealed the potential mechanism by which hypoxia-induced OPN + GAMs promote the mesenchymal transition in GBM cells and demonstrated the therapeutic potential of targeting OPN to enhance TMZ treatment effectiveness.
Countstar Connection
Within the study, Countstar (model not specified) measured fluorescence-based cell measurements in the study's cell samples during sample-quality assessment.
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