SCIENTIFIC EVIDENCE

Self-renewing human naïve pluripotent stem cells dedifferentiate in 3D culture and form blastoids spontaneously

Nature Communications

Mingyue Guo, Jinyi Wu, Chuanxin Chen, Xinggu Wang, An Gong, Wei Guan, Rowan M. Karvas, Kexin Wang, Mingwei Min, Yixuan Wang, Thorold W. Theunissen, Shaorong Gao, José C. R. Silva

Publication Overview

Key findings, Countstar context, and access to the original paper.

2024

3D Culture

Mira FL

Key Finding

This study shows that self-renewing human naïve pluripotent stem cells can spontaneously form blastoids in 3D suspension culture, providing an in vitro model for investigating early human development.

Countstar Connection

Countstar Mira FL with AO/PI fluorescence staining was used to determine cell number and assess cell viability during blastoid generation and single-cell RNA sequencing sample preparation.

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