SCIENTIFIC EVIDENCE

Human induced-T-to-natural killer cells have potent anti-tumour activities.

Biomarker research
Jiang Z, Qin L, Tang Y, Liao R, Shi J, He B, Li S, Zheng D, Cui Y, Wu Q, Long Y, Yao Y, Wei Z, Hong Q, Wu Y, Mai Y, Gou S, Li X, Weinkove R, Norton S, Luo W, Feng W, Zhou H, Liu Q, Chen J, Lai L, Chen X, Pei D, Graf T, Liu X, Li Y, Liu P, Zhang Z, Li P.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2022
Cancer Research
Immunology
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Key Finding
ITNKs contained a diverse TCR repertoire; downregulated T cell-associated genes such as TCF7 and LEF1; and expressed high levels of NK cell lineage-associated genes. The novel ITNKs thus may be a promising novel cell source for cancer immunotherapy.
Countstar Connection
The study's cell samples underwent cell-count assessment with Countstar (model not specified) during sample-quality assessment.
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