Heat stress activates YAP/TAZ to induce the heat shock transcriptome.
Nature cell biology
Luo M, Meng Z, Moroishi T, Lin KC, Shen G, Mo F, Shao B, Wei X, Zhang P, Wei Y, Guan KL.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2020
Single-Cell Analysis
No items found.
Key Finding
The study shows that heat stress induces a strong and rapid YAP dephosphorylation and activation. The observations also reveal a potential combinational therapy involving hyperthermia and targeting of the Hippo pathway.
Countstar Connection
The research obtained cell-count measurements from the study's cell samples using Countstar (model not specified) during quality assessment for the study's single-cell analysis.
