H3K18 lactylation potentiates microglial polarization via the TLR4 pathway in diabetes-induced cognitive impairment.
JCI insight
Yang Y, Chen F, Song L, Yu L, Zhang J, Zhang B.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Cell Counting & Viability
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Key Finding
The findings show that lactic acid levels were significantly greater in the brains of T2DM mice and high glucose-treated microglia than in those of their corresponding controls, which increased the level of Pan-Kla.
Countstar Connection
Countstar (model not specified) measured cell numbers in the study's cell samples during sample-quality assessment.