SCIENTIFIC EVIDENCE

Gastric Cancer Actively Remodels Mechanical Microenvironment to Promote Chemotherapy Resistance via MSCs-Mediated Mitochondrial Transfer.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

He X, Zhong L, Wang N, Zhao B, Wang Y, Wu X, Zheng C, Ruan Y, Hou J, Luo Y, Yin Y, He Y, Xiang AP, Wang J.

Publication Overview

Key findings, Countstar context, and access to the original paper.

2024

Bioprocessing

Cancer Research

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Key Finding

In summary, these indicate that matrix stiffness could be used as an indicator to identify chemotherapy resistance, and targeting mechanical-related pathway could effectively alleviate OXA resistance and improve therapeutic efficacy.

Countstar Connection

The study obtained cell-count and viability measurements from the study's cell samples with Countstar Rigel S2 during quality assessment in the 2024 Advanced science study.

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