Fusobacterium nucleatum Facilitates Apoptosis, ROS Generation, and Inflammatory Cytokine Production by Activating AKT/MAPK and NF- κ B Signaling Pathways in Human Gingival Fibroblasts.

These findings suggest that F. nucleatum inhibits GF proliferation and promotes cell apoptosis, ROS generation, and inflammatory cytokine production partly by activating the AKT/MAPK and NF- κ B signaling pathways.

Using Countstar (model not specified), the researchers measured cell numbers in the study's cell samples during growth assessment for the immune-cell research.