Fludarabine as an Adjuvant Improves Newcastle Disease Virus-Mediated Antitumor Immunity in Hepatocellular Carcinoma.
Molecular therapy oncolytics
Meng G, Fei Z, Fang M, Li B, Chen A, Xu C, Xia M, Yu D, Wei J.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2019
Cancer Research
Immunology
Microbiology
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Key Finding
The aforementioned effects of fludarabine significantly improved NDV-mediated antitumor immunity and prolonged survival in mouse model of HCC. The findings indicate the utility of fludarabine as an adjuvant for oncolytic anticancer viro-immunotherapy.
Countstar Connection
Cell number and viability were quantified in the study's cell samples with Countstar (model not specified) during quality assessment for the cancer-model experiments.
