SCIENTIFIC EVIDENCE

Single dose of 5 Gy can damage erythrocytes and consequently induces lymphocyte depletion in spleen and circulating blood

Frontiers in Immunology
Peimeng You, Xiaohang Qin, Yinghui Li, Huiling Ye, Yuhui Zhao, Guangshan Wang, Cuimeng Tian, Shuo Yin, Junyu Li, Teng Ma, Feng-Ming Spring Kong, Jian-Yue Jin

Publication Overview

Key findings, Countstar context, and access to the original paper.
2026
Cell Counting & Viability
Single-Cell Analysis
Mira BF
Key Finding
The study shows that a single 5-Gy radiation dose damages erythrocytes and promotes their clearance by splenic macrophages, with accompanying depletion of lymphocytes in blood and spleen. The findings connect red-cell injury and immune-cell loss as linked components of radiation-induced hematologic toxicity.
Countstar Connection
Complete blood cell counts after irradiation were determined with a Countstar Mira BF automated hematology analyzer to quantify erythrocyte and leukocyte changes.
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