SCIENTIFIC EVIDENCE

FABP4-mediated lipid droplet accumulation drives epithelial-mesenchymal transition and aggravates alveolar epithelial barrier disruption.

Clinical and translational medicine

Shen Z, Qi Y, Chu M, Wu M, Feng C, Li X, Liu Z, Si L, Wang Y, Zhang J, Lu X, Lu P.

Publication Overview

Key findings, Countstar context, and access to the original paper.

2026

Stem Cell Research

No items found.

Key Finding

FABP4 activation enhanced FA metabolism and promoted EMT, which played a critical role in epithelial barrier dysfunction. Targeting FABP4 or lipid droplets accumulation may offer therapeutic potential for CPB-associated ARDS.

Countstar Connection

Researchers used Countstar (model not specified) to assess cell numbers in the study's cell samples during sample-quality assessment.

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