SCIENTIFIC EVIDENCE

Exploring the co-morbid relationship between Alzheimer's disease and lung cancer in the 5xFAD transgenic mouse model.

Animal models and experimental medicine
Li M, Wu X, Jiang L, Liu M, Yanju G, Li X, Tian F, Ye F, Wang J, Wang S, Qin C, Zhang L.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2025
Cancer Research
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Key Finding
The findings revealed a significant reduction in lung tumor incidence in the AD group compared with that in the wild-type (WT) group. The indicated a close association between AD-induced inhibition of lung tumor progression and iron homeostasis imbalance and increased oxidative stress.
Countstar Connection
For the study's cell samples, researchers obtained cell-concentration measurements with Countstar (model not specified) before single-cell analysis for the cancer-model experiments.
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