SCIENTIFIC EVIDENCE

Erucic Acid, Derived by Lactobacillus Crispatus, Induces Ferroptosis in Cervical Cancer Organoids Through the PPAR-δ Signaling Pathway.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhen Q, Xu Y, Xu Y, Liu X, Zhang Y, Ye D, Han S, Liu S, Zhang Y.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2025
3D Culture
Cancer Research
Organoid Culture
Single-Cell Analysis
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Key Finding
Excessive enhancement of FAO can generate large amounts of H 2 O 2 and O 2 -, known as ROS. Therefore, L. crispatus and erucic acid show potential as novel adjuvant therapeutic agents in the treatment of cervical cancer.
Countstar Connection
Cell concentration was quantified in the study's cell samples with Countstar Rigel S2 before single-cell analysis for the organoid or 3D-culture experiments.
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