Engineering CCR2/IFN-γ overexpression in enucleated mesenchymal stem cells enhances therapy for rheumatoid arthritis.
Communications biology
Sui Y, Pu Z, Yang N, Luo Y, Sa Y, Qi Q, Tan L, Yan Y, Si W.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Stem Cell Research
No items found.
Key Finding
Compared to MSCs, En-MSCs C/I demonstrated superior migration to injured joints and unique regulatory signature for cartilage regeneration. The study suggests that En-MSCs C/I may offer enhanced therapeutic effects for RA-related cartilage damage while maintaining favorable safety profiles.
Countstar Connection
Researchers relied on Countstar (model not specified) for cell-count and viability measurements in the study's cell samples during quality assessment in the 2025 Communications biology study.
