Engineered CCR2 Cell Membrane-Wrapped Cepharanthine Liposomes for Potential Targeted Attenuation of Acute Lung Injury.
Cells
Qing Y, Zhao W, Xue L, Luo Y, Gao Y, Sun X, Li F, Dai L, Mo J, Xu G, Bi Z, Yang S, Hee WT, Li J, Leng L.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2026
Bioprocessing
Immunology
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Key Finding
CEP@LP-M CCR2 could suppress M1 macrophage polarization, which led to a marked decrease in iNOS and an increase in Arg1. It upregulated the expression of junctional proteins E-cadherin and Occludin, indicating potential recovery of the pulmonary epithelial barrier.
Countstar Connection
In this work, Countstar (model not specified) measured cell numbers in the study's cell samples during quality assessment for the reported research.