SCIENTIFIC EVIDENCE

Elevated expression of the rhythm gene NFIL3 promotes the progression of TNBC by activating NF-κB signaling through suppression of NFKBIA transcription.

Journal of experimental & clinical cancer research: CR

Yang W, Li J, Zhang M, Yu H, Zhuang Y, Zhao L, Ren L, Gong J, Bi H, Zeng L, Xue Y, Yang J, Zhao Y, Wang S, Gao S, Fu Z, Li D, Zhang J, Wang T, Shan M, Tang B, Li X.

Publication Overview

Key findings, Countstar context, and access to the original paper.

2022

Cancer Research

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Key Finding

The findings demonstrate that NFIL3 promotes the proliferation and metastasis of TNBC cells in vitro and in vivo, and higher expression of NFIL3 is associated with poor prognosis of patients with TNBC.

Countstar Connection

The researchers relied on Countstar (model not specified) to measure cell numbers in the study's cell samples during growth assessment for the reported research.

View paper ↗

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