SCIENTIFIC EVIDENCE

Dynamic transition of Tregs to cytotoxic phenotype amid systemic inflammation in Graves' ophthalmopathy.

JCI insight
Liu Z, Ke SR, Shi ZX, Zhou M, Sun L, Sun QH, Xiao B, Wang DL, Huang YJ, Lin JS, Wang HS, Zhang QK, Pan CN, Liang XW, Chen RX, Mao Z, Lin XC.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2024
Immunology
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Key Finding
The findings reveal the dynamic changes in immune landscape during GO progression and provide direct insights into the instability and phenotypic transition of Treg, offering potential targets for therapeutic intervention and prevention of autoimmune diseases.
Countstar Connection
For the study's cell samples, Countstar Rigel S2 provided cell-count and viability measurements before downstream analysis in the 2024 JCI insight study.
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