Dynamic transcriptome and chromatin architecture in granulosa cells during chicken folliculogenesis.

Chromatin architecture was extensively reorganized alongside transcriptomic changes in chicken granulosa cells across folliculogenesis. The study documented compartment shifts, changes in topologically associating domains, and rewiring of long-range promoter-enhancer interactions, providing a resource for avian reproductive research.

Cell-count and viability assessment in the study's cell samples used Countstar Rigel S2 before single-cell analysis for the study's single-cell analysis.