Dynamic changes of molecular pattern and cellular subpopulation in puncture-induced tendon injury model.
iScience
Huang Z, Li Z, Ruan D, Xu Y, Cai H, Liu H, Jin H, He P, Fei Y, Huang J, Wang C, Chen X, Jiang J, Shen W.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Single-Cell Analysis
Stem Cell Research
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Key Finding
In this study, the authors established a puncture-induced tendon injury model to investigate the molecular patterns and cellular subpopulations involved in early tendon injury across multiple time points. Single-cell RNA sequencing further revealed eight myeloid cell types and seven mesenchymal cell types participating in the tendon repair process.
Countstar Connection
The researchers measured cell number and viability in the study's cell samples with Countstar (model not specified) before single-cell analysis in the 2025 iScience study.