Dual-Pronged Lipid Nanocarriers Promote Immunotherapy for TNBC by Inducing Immunogenic Cell Death and Activating Lymphoid Immune Cells.

Of note, PTX Emul combined with CHA-SME augmented the immunotherapeutic effects through highly efficient ICD induction within the tumor microenvironment of 4T1 orthotopic tumor, the potent DC maturation, and the effective activation of T cell-based antitumor immunity, resulting in a substantial enhancement in the inhibition of 4T1 orthotopic tumors and, notably, a reduction in lung metastasis.

For the study's cell samples, researchers obtained cell-count measurements with Countstar Mira FL during quality assessment for the immune-cell research.