Dosage and organic acid residue of myelin oligodendrocyte glycoprotein 35-55 peptide influences immunopathology and development of Bacillus Calmette-Guérin induced experimental autoimmune encephalomyelitis.

The findings show that BCG can be effectively used to induce EAE with similar incidence and severity as heat-killed H37Ra, contingent upon the appropriate MOG 35-55 peptide dose. The authors highlighted the feasibility of applying BCG to the establishment of EAE for the first time.

For the study's cell samples, Countstar (model not specified) provided cell-count measurements during quality assessment in the 2025 Experimental animals study.