Disruption of Morrbid alleviates autoinflammatory osteomyelitis in Pstpip2-deficient mice.
Disease models & mechanisms
Huo Q, Ding J, Zhou H, Wang Y, Wang S, He H, Cai LC, Liu J, Dong G, Cai Z.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Single-Cell Analysis
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Key Finding
Using murine models, this study profiles the pathological cell landscape of CRMO by single-cell analysis and suggests that reducing the lifespan of inflammatory myeloid cells by targeting Morrbid can be an effective therapy for chronic osteomyelitis.
Countstar Connection
Using Countstar Rigel S2, the study assessed cell number and viability in the study's cell samples before single-cell analysis in the 2025 Disease models & mechanisms study.
